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The missing
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Multiple Sclerosis
Glossary
“ Human beings in their entirety and as a whole “
MULTIPLE SCLEROSIS, DEFINITION .
Multiple sclerosis is also called slow virus ( the virus is latent in
the body where, drawing nourishment out of it, it develops causing the
onset of the actual pathology) .
- Definition
Multiple sclerosis (MS) is a disorder of the Central Nervous System (CNS)
(1) N.B.(the number indicates the glossary of specific words to
the end of article), of unknown etiology ( all the causes underlying a
pathology), probably autoimmune (2), defined clinically by
typical symptoms, signs and disease progression defined as
relapsing-remitting course (periods of riacutization alternating to
periods of rare remission of symptoms) characterized by scattered areas
of inflammation , demyelination (loss of myelin, that is the
proteo-lipidic coat of neuronal axons) (3) , and axonal injury (
such a injury eliminates the possibility of communication and, therefore,
the control on the muscular system and peripheral nervous system (4)
by CNS). The areas of tissue damage are localized to the brain
( cerebrum and cerebellum) optic nerves (nerves departing from brain and
directed to the eyes; they are essential to the vision), and spinal cord
(5).
- Clinical manifestation.
Symptoms onset occurs between ages 15 and 50 years. The outbursts of
inflammatory demyelination (poussées or recidivations) are characterized
by symptoms of neurologic nature. However, the symptoms are very
variable and heterogeneous. In younger patients the disease usually
starts with subacute or acute onset of neurologic symptoms and signs
most often reflecting disease in optic nerves , pyramidal tracts (two
voluminous axon bundles from cerebral cortex and descending up to the
spinal cord where make a contact, Synapse, with neurons engaged in motor
control), cerebellum (part of CNS responsible of superior motor control
of the whole body), central vestibular system (part of CNS responsible
of the body equilibrium). Therefore, clinical visual signs and symptoms
include loss of visual acuity , diplopia (double vision) monocular
ipovisus (loss of vision from one eye), motor symptoms as gait disorders
secondary to the spastic paraparesis (6), (7), and
mioclonus (8) associated to ipoasthenia ( loss of muscle strength)
and loss of dexterity.
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